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Title: Structural Variation Of The Human Genome PDF, ePub eBook

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Abstractthere is growing appreciation that the human genome contains significant numbers of structural rearrangements such as insertions deletions inversions and large tandem repeats recent studies have defined approximately 5 of the human genome as structurally variant in the normal population involving more than 800 independent genesstructural variation also genomic structural variation is the variation in structure of an organisms chromosome it consists of many kinds of variation in the genome of one species and usually includes microscopic and submicroscopic types such as deletions duplications copy number variants insertions inversions and translocationstuzun e et al fine scale structural variation of the human genome nature genet 37 727732 2005structural variation of the human genome mechanisms assays and role in male infertility claudia mb carvalho department of molecular and human genetics baylor college of medicine houston tx usa feng zhangtuzun e et al fine scale structural variation of the human genome nat genet 37 727 32 2005 wong kk et al a comprehensive analysis of common copy number variations in the human genome am j hum genet 80 91 104 2007

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